The dynamics of chromatin remodeling at promoters.
The nucleosome, the structural unit of chromatin, is known to play a central role in regulating gene transcription from promoters. The last seven years have spawned a vast amount of data on the enzymes that remodel and modify nucleosomes and the rules governing how transcription factors interact wit...
| Main Author: | |
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| Format: | Journal article |
| Language: | English |
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2005
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| _version_ | 1797085577689956352 |
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| author | Mellor, J |
| author_facet | Mellor, J |
| author_sort | Mellor, J |
| collection | OXFORD |
| description | The nucleosome, the structural unit of chromatin, is known to play a central role in regulating gene transcription from promoters. The last seven years have spawned a vast amount of data on the enzymes that remodel and modify nucleosomes and the rules governing how transcription factors interact with the epigenetic code on histones. Yet despite this effort, there has yet to emerge a unifying mechanism by which nucleosomes are remodeled during gene regulation. Recent advances have allowed nucleosome dynamics on promoters to be studied in real time, dramatically changing how we think about gene regulation on chromatin templates. |
| first_indexed | 2024-03-07T02:10:40Z |
| format | Journal article |
| id | oxford-uuid:a0881eda-6314-49ea-bf3b-1a8f7577677c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:10:40Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:a0881eda-6314-49ea-bf3b-1a8f7577677c2022-03-27T02:06:14ZThe dynamics of chromatin remodeling at promoters.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a0881eda-6314-49ea-bf3b-1a8f7577677cEnglishSymplectic Elements at Oxford2005Mellor, JThe nucleosome, the structural unit of chromatin, is known to play a central role in regulating gene transcription from promoters. The last seven years have spawned a vast amount of data on the enzymes that remodel and modify nucleosomes and the rules governing how transcription factors interact with the epigenetic code on histones. Yet despite this effort, there has yet to emerge a unifying mechanism by which nucleosomes are remodeled during gene regulation. Recent advances have allowed nucleosome dynamics on promoters to be studied in real time, dramatically changing how we think about gene regulation on chromatin templates. |
| spellingShingle | Mellor, J The dynamics of chromatin remodeling at promoters. |
| title | The dynamics of chromatin remodeling at promoters. |
| title_full | The dynamics of chromatin remodeling at promoters. |
| title_fullStr | The dynamics of chromatin remodeling at promoters. |
| title_full_unstemmed | The dynamics of chromatin remodeling at promoters. |
| title_short | The dynamics of chromatin remodeling at promoters. |
| title_sort | dynamics of chromatin remodeling at promoters |
| work_keys_str_mv | AT mellorj thedynamicsofchromatinremodelingatpromoters AT mellorj dynamicsofchromatinremodelingatpromoters |