Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin.
The growth of blood and lymphatic vasculature is mediated in part by secreted polypeptides of the vascular endothelial growth factor (VEGF) family. The prototype VEGF binds VEGF receptor (VEGFR)-1 and VEGFR-2 and is angiogenic, whereas VEGF-C, which binds to VEGFR-2 and VEGFR-3, is either angiogenic...
Auteurs principaux: | Enholm, B, Karpanen, T, Jeltsch, M, Kubo, H, Stenback, F, Prevo, R, Jackson, D, Yla-Herttuala, S, Alitalo, K |
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Format: | Journal article |
Langue: | English |
Publié: |
2001
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