| Shrnutí: | <h4>Background and Purpose</h4> <p>To perform a systematic review regarding the use of stereotactic ablative radiotherapy (SABR) for the re-irradiation of recurrent malignant disease within the pelvis, to guide the clinical implementation of this technique.</p> <h4>Material and Methods</h4> <p>A systematic search strategy was adopted using the MEDLINE, EMBASE and Cochrane Library databases.</p> <h4>Results</h4> <p>194 articles were identified, of which 17 were appropriate for inclusion. Studies were small and data largely retrospective. In total, 211 patients are reported to have received pelvic SABR re-irradiation. Dose and fractionation schedules and re-irradiated volumes are highly variable. Little information is provided regarding organ at risk constraints adopted in the re-irradiation setting. Treatment appears well-tolerated overall, with nine grade 3 and six grade 4 toxicities amongst thirteen re-irradiated patients. Local control at one year ranged from 51% to 100%. Symptomatic improvements were also noted.</p> <h4>Conclusions</h4> <p>For previously irradiated patients with recurrent pelvic disease, SABR re-irradiation could be a feasible intervention for those who otherwise have limited options. Evidence to support this technique is limited but shows initial promise. Based on the available literature, suggestions for a more formal SABR re-irradiation pathway are proposed. Prospective studies and a multidisciplinary approach are required to optimise future treatment.</p>
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