Ten-year persistence and evolution of Plasmodium falciparum antifolate and anti-sulfonamide resistance markers pfdhfr and pfdhps in three Asian countries

<p><strong>Background</strong> The amplification of <i>GTP cyclohydrolase 1 (pfgch1)</i> in <i>Plasmodium falciparum</i> has been linked to the upregulation of the <i>pfdhfr</i> and <i>pfdhps</i> genes associated with resistance to th...

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Hlavní autoři: Srisutham, S, Madmanee, W, Kouhathong, J, Sutawong, K, Tripura, R, Peto, TJ, van der Pluijm, RW, Callery, JJ, Dysoley, L, Mayxay, M, Newton, PN, Pongvongsa, T, Hongvanthong, B, Day, NPJ, White, NJ, Dondorp, AM, Imwong, M
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2022