Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12

Molecular mechanisms for enhancing the antigenicity of the carbohydrate epitope of the broadly neutralizing anti-HIV-1 antibody 2G12

Bibliografski detalji
Glavni autori:	Fulton, Z, Doores, K, Scanlan, C, Wormald, M, Dwek, R, Wilson, I, Davis, B
Format:	Journal article
Jezik:	English
Izdano:	2009

Slični predmeti

The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
od: Scanlan, C, i dr.
Izdano: (2003)

A 'non-self' mimic of the natural epitope of anti-HIV antibody 2G12 shows enhanced antigenicity
od: Doores, K, i dr.
Izdano: (2009)

Polysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.
od: Dunlop, D, i dr.
Izdano: (2010)

A novel form of carbohydrate recognition. The broadly neutralizing anti-HIV-1 antibody 2G12 recognizes a cluster of a1-2 mannose residues on the outer face of GP120
od: Rudd, P, i dr.
Izdano: (2002)

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.
od: Kong, R, i dr.
Izdano: (2012)

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data
od: Ferguson, Andrew L., i dr.
Izdano: (2014)

Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies
od: Krumm, S, i dr.
Izdano: (2016)

Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope
od: Dunlop, D, i dr.
Izdano: (2009)

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.
od: Astronomo, R, i dr.
Izdano: (2008)

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
od: Pejchal, R, i dr.
Izdano: (2011)

Glycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodies.
od: Pritchard, L, i dr.
Izdano: (2015)

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
od: Scanlan, C, i dr.
Izdano: (2002)

Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
od: Scanlan, C, i dr.
Izdano: (2007)

Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies
od: Haynes, BF, i dr.
Izdano: (2022)

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity.
od: Doores, K, i dr.
Izdano: (2010)

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
od: Sok, Devin, i dr.
Izdano: (2014)

Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies
od: Borrow, P, i dr.
Izdano: (2017)

Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
od: Oakes, V, i dr.
Izdano: (2018)

Enhanced clearance of HIV-1-infected cells by broadly neutralizing antibodies against HIV-1 in vivo
od: Lu, C.-L., i dr.
Izdano: (2017)

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
od: Steichen, Jon M., i dr.
Izdano: (2017)

Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies
od: Moody, M, i dr.
Izdano: (2016)

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies
od: Labranche, CC, i dr.
Izdano: (2018)

Optimizing immunization protocols to elicit broadly neutralizing antibodies
od: Sprenger, Kayla G, i dr.
Izdano: (2021)

Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies
od: Karplus, Martin, i dr.
Izdano: (2018)

Epitopes of the CD4 antigen and HIV infection.
od: Sattentau, Q, i dr.
Izdano: (1986)

Cellular and humoral antigenic epitopes in HIV and SIV.
od: Nixon, D, i dr.
Izdano: (1992)

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
od: Calarese, D, i dr.
Izdano: (2003)

Refocusing the Antibody Response: The Use of an Antibody-Masking Technique to Elicit Broadly Neutralizing Antibodies
od: Wan, D, i dr.
Izdano: (2011)

Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site
od: Conti, Simone, i dr.
Izdano: (2021)

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort.
od: Landais, E, i dr.
Izdano: (2016)

Antibody neutralization of HIV-1.
od: Poignard, P, i dr.
Izdano: (1996)

Neutralization of HIV-1 by antibody.
od: Sattentau, Q
Izdano: (1996)

Carbohydrate antigens /
od: Garegg, Per J., i dr.
Izdano: (1993)

Development of Broadly Neutralizing Antibody Responses in a Large Sub-Sahara African HIV Primary Infection Cohort
od: Landais, E, i dr.
Izdano: (2013)

Neutralizing anti-HIV antibodies develop in a humanized
od: Seung, E., i dr.
Izdano: (2013)

Antigenic mimicry of the HIV envelope by AIDS-Associated pathogens
od: Dunlop, D, i dr.
Izdano: (2008)

Lipid Binding: A Necessary Evil for Broadly Neutralizing Anti-gp41 Antibodies?
od: Scherer, E, i dr.
Izdano: (2008)

Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.
od: Rolland, M, i dr.
Izdano: (2008)

Learning patterns of HIV-1 resistance to broadly neutralizing antibodies with reduced subtype bias using multi-task learning
od: Igiraneza, AB, i dr.
Izdano: (2024)

Potent autologous and heterologous neutralizing antibody responses occur in HIV-2 infection across a broad range of infection outcomes.
od: de Silva, T, i dr.
Izdano: (2012)