Cleavage specificities of the brother and sister proteases Lys-C and Lys-N.
Understanding of protease specificity is essential in proteomics strategies to correctly compare peptide fragmentation spectra with spectra predicted from data extracted from sequence databases. Here we evaluate the specificities of two proteolytic enzymes Lys-C and Lys-N, which cleave peptide-bonds...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2010
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| _version_ | 1797085738716626944 |
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| author | Raijmakers, R Neerincx, P Mohammed, S Heck, A |
| author_facet | Raijmakers, R Neerincx, P Mohammed, S Heck, A |
| author_sort | Raijmakers, R |
| collection | OXFORD |
| description | Understanding of protease specificity is essential in proteomics strategies to correctly compare peptide fragmentation spectra with spectra predicted from data extracted from sequence databases. Here we evaluate the specificities of two proteolytic enzymes Lys-C and Lys-N, which cleave peptide-bonds at, respectively, the C- and N-terminal side of a lysine residue. |
| first_indexed | 2024-03-07T02:12:13Z |
| format | Journal article |
| id | oxford-uuid:a10aae69-705b-4c59-8c34-e00a3744331f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:12:13Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:a10aae69-705b-4c59-8c34-e00a3744331f2022-03-27T02:10:10ZCleavage specificities of the brother and sister proteases Lys-C and Lys-N.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a10aae69-705b-4c59-8c34-e00a3744331fEnglishSymplectic Elements at Oxford2010Raijmakers, RNeerincx, PMohammed, SHeck, AUnderstanding of protease specificity is essential in proteomics strategies to correctly compare peptide fragmentation spectra with spectra predicted from data extracted from sequence databases. Here we evaluate the specificities of two proteolytic enzymes Lys-C and Lys-N, which cleave peptide-bonds at, respectively, the C- and N-terminal side of a lysine residue. |
| spellingShingle | Raijmakers, R Neerincx, P Mohammed, S Heck, A Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title | Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title_full | Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title_fullStr | Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title_full_unstemmed | Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title_short | Cleavage specificities of the brother and sister proteases Lys-C and Lys-N. |
| title_sort | cleavage specificities of the brother and sister proteases lys c and lys n |
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