An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1.
Hv1 voltage-gated proton channels mediate rapid and selective transmembrane H(+) flux and are gated by both voltage and pH gradients. Selective H(+) transfer in membrane proteins is commonly achieved by Grotthuss proton 'hopping' in chains of ionizable amino acid side chains and intraprote...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2010
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