Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques

<p><strong>Aims:</strong> Inflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.</p>...

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Detaylı Bibliyografya
Asıl Yazarlar: Edsfeldt, A, Swart, M, Singh, P, Dib, L, Sun, J, Cole, JE, Park, I, Al-Sharify, D, Persson, A, Nitulescu, M, Das Neves Borges, P, Kassiteridi, C, Goddard, ME, Lee, R, Volkov, P, Orho-Melander, M, Maegdefessel, L, Nilsson, J, Udalova, I, Goncalves, I, Monaco, C
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Oxford University Press 2022