Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.

Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.

The Jumonji C lysine demethylases (KDMs) are 2-oxoglutarate- and Fe(II)-dependent oxygenases. KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(ϵ)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. Despite reports stating...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Walport, L, Hopkinson, R, Vollmar, M, Madden, S, Gileadi, C, Oppermann, U, Schofield, C, Johansson, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2014

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