Hammerhead ribozyme specifically inhibits vascular endothelial growth factor gene expression in a human hepatocellular carcinoma cell line.

Hammerhead-type ribozymes are often utilized to suppress the expression of target genes. We evaluated the efficacy of an anti-vascular endothelial growth factor (VEGF) hammerhead-type ribozyme against GUC at exon 1 of the VEGF gene in a cell-free system (in vitro) as well as in the hepatocellular ca...

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Bibliografski detalji
Glavni autori: Morino, F, Tokunaga, T, Tsuchida, T, Handa, A, Nagata, J, Tomii, Y, Kijima, H, Yamazaki, H, Watanabe, N, Matsuzaki, S, Ueyama, Y, Nakamura, M
Format: Journal article
Jezik:English
Izdano: 2000