Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Obstacles to developing an HIV-1 vaccine include extensive viral diversity and lack of correlates of protective immunity. High mutation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immune pressure, including HIV-1-specific CTLs that select viral variants...

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Hlavní autoři:	Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S
Médium:	Journal article
Jazyk:	English
Vydáno:	2011

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Autor Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S

Vydáno 2011

Journal article

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. Autor Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S

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