Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Obstacles to developing an HIV-1 vaccine include extensive viral diversity and lack of correlates of protective immunity. High mutation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immune pressure, including HIV-1-specific CTLs that select viral variants...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2011

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. gan Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S

Cyhoeddwyd 2011

Journal article

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China. gan Dong, T, Zhang, Y, Xu, K, Yan, H, James, I, Peng, Y, Blais, M, Gaudieri, S, Chen, X, Lun, W, Wu, H, Qu, W, Rostron, T, Li, N, Mao, Y, Mallal, S, Xu, X, McMichael, A, John, M, Rowland-Jones, S

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