Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China
Obstacles to developing an HIV-1 vaccine include extensive viral diversity and lack of correlates of protective immunity. High mutation rates allow HIV-1 to adapt rapidly to selective forces such as antiretroviral therapy and immune pressure, including HIV-1-specific CTLs that select viral variants...
Príomhchruthaitheoirí: | , , , , , , , , , , , , , , , , , , , |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2011
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Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China.
Foilsithe / Cruthaithe 2011
Journal article