Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.

Several factors contribute to the high mortality attributed to severe infections in resource-limited settings. While improvements in survival and processes of care have been made in high-income settings among patients with severe conditions, such as sepsis, guidelines necessary for achieving these i...

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Main Authors: Jacob, S, Lim, M, Banura, P, Bhagwanjee, S, Bion, J, Cheng, A, Cohen, H, Farrar, J, Gove, S, Hopewell, P, Moore, C, Roth, C, West, T
Format: Journal article
Language:English
Published: BioMed Central 2013
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author Jacob, S
Lim, M
Banura, P
Bhagwanjee, S
Bion, J
Cheng, A
Cohen, H
Farrar, J
Gove, S
Hopewell, P
Moore, C
Roth, C
West, T
author_facet Jacob, S
Lim, M
Banura, P
Bhagwanjee, S
Bion, J
Cheng, A
Cohen, H
Farrar, J
Gove, S
Hopewell, P
Moore, C
Roth, C
West, T
author_sort Jacob, S
collection OXFORD
description Several factors contribute to the high mortality attributed to severe infections in resource-limited settings. While improvements in survival and processes of care have been made in high-income settings among patients with severe conditions, such as sepsis, guidelines necessary for achieving these improvements may lack applicability or have not been tested in resource-limited settings. The World Health Organization's recent publication of the Integrated Management of Adolescent and Adult Illness District Clinician Manual provides details on how to optimize management of severely ill, hospitalized patients in such settings, including specific guidance on the management of patients with septic shock and respiratory failure without shock. This manuscript provides the context, process and underpinnings of these sepsis guidelines. In light of the current deficits in care and the limitations associated with these guidelines, the authors propose implementing these standardized best practice guidelines while using them as a foundation for sepsis research undertaken in, and directly relevant to, resource-limited settings.
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spelling oxford-uuid:a168da3a-2a0e-4068-9ea6-193845b8985d2022-03-27T02:13:05ZIntegrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a168da3a-2a0e-4068-9ea6-193845b8985dEnglishSymplectic Elements at OxfordBioMed Central2013Jacob, SLim, MBanura, PBhagwanjee, SBion, JCheng, ACohen, HFarrar, JGove, SHopewell, PMoore, CRoth, CWest, TSeveral factors contribute to the high mortality attributed to severe infections in resource-limited settings. While improvements in survival and processes of care have been made in high-income settings among patients with severe conditions, such as sepsis, guidelines necessary for achieving these improvements may lack applicability or have not been tested in resource-limited settings. The World Health Organization's recent publication of the Integrated Management of Adolescent and Adult Illness District Clinician Manual provides details on how to optimize management of severely ill, hospitalized patients in such settings, including specific guidance on the management of patients with septic shock and respiratory failure without shock. This manuscript provides the context, process and underpinnings of these sepsis guidelines. In light of the current deficits in care and the limitations associated with these guidelines, the authors propose implementing these standardized best practice guidelines while using them as a foundation for sepsis research undertaken in, and directly relevant to, resource-limited settings.
spellingShingle Jacob, S
Lim, M
Banura, P
Bhagwanjee, S
Bion, J
Cheng, A
Cohen, H
Farrar, J
Gove, S
Hopewell, P
Moore, C
Roth, C
West, T
Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title_full Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title_fullStr Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title_full_unstemmed Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title_short Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research.
title_sort integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource limited settings the necessity to augment new guidelines with future research
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