Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.

Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors.

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We report the isolation and structural determination of fourteen iminosugars, containing five pyrrolizidines and five indolizidines, from Castanospermum australe. The structure of a new alkaloid was elucidated by spectroscopic methods as 6,8-diepi-castanospermine (13). Our side-by-side comparison be...

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Main Authors: Kato, A, Hirokami, Y, Kinami, K, Tsuji, Y, Miyawaki, S, Adachi, I, Hollinshead, J, Nash, R, Kiappes, J, Zitzmann, N, Cha, J, Molyneux, R, Fleet, G, Asano, N
Format: Journal article
Jezik:English
Izdano: Elsevier 2015

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