The influence of tumour microenvironmental factors on the efficacy of cisplatin and novel platinum(IV) complexes.

The chemotherapeutic drug cisplatin is an important treatment for many types of solid tumours, in particular non-small cell lung cancer (NSCLC). Platinum(IV) complexes offer several advantages to cisplatin due to their requirement for reduction to the active platinum(II) form to elicit cytotoxicity....

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Autori principali: Mellor, H, Snelling, S, Hall, MD, Modok, S, Jaffar, M, Hambley, T, Callaghan, R
Natura: Journal article
Lingua:English
Pubblicazione: 2005