A robust clustering algorithm for identifying problematic samples in genome-wide association studies

High-throughput genotyping arrays provide an efficient way to survey single nucleotide polymorphisms (SNPs) across the genome in large numbers of individuals. Downstream analysis of the data, for example in genome-wide association studies (GWAS), often involves statistical models of genotype frequen...

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Bibliographic Details
Main Authors: Bellenguez, C, Strange, A, Freeman, C, Wellcome Trust Case Control Consortium 2, Donnelly, P, Spencer, C
Other Authors: The International Society for Computational Biology
Format: Journal article
Language:English
Published: Oxford University Press 2012
Subjects: