A robust clustering algorithm for identifying problematic samples in genome-wide association studies
High-throughput genotyping arrays provide an efficient way to survey single nucleotide polymorphisms (SNPs) across the genome in large numbers of individuals. Downstream analysis of the data, for example in genome-wide association studies (GWAS), often involves statistical models of genotype frequen...
Main Authors: | Bellenguez, C, Strange, A, Freeman, C, Wellcome Trust Case Control Consortium 2, Donnelly, P, Spencer, C |
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Other Authors: | The International Society for Computational Biology |
Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2012
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Subjects: |
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