Phase 2a, open-label, dose-escalating, multi-center pharmacokinetic study of favipiravir (T-705) in combination with oseltamivir in patients with severe influenza
Background The pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data are also needed to determine dosage selection for favipiravir trials in COVID-19. Methods In this dose-escalating study, favipiravir pharmacokinetics and tolerabili...
Main Authors: | Wang, Y, Zhong, W, Salam, A, Tarning, J, Zhan, Q, Huang, J-A, Weng, H, Bai, C, Ren, Y, Yamada, K, Wang, D, Guo, Q, Fang, Q, Tsutomu, S, Zou, X, Li, H, Gillesen, A, Castle, L, Chen, C, Zhen, J, Lu, B, Duan, J, Guo, L, Jiang, J, Cao, R, Fan, G, Li, J, Hayden, FG, Wang, C, Horby, P, Cao, B |
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格式: | Journal article |
語言: | English |
出版: |
Elsevier
2020
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