Hippocampal theta in rats under urethane: generators and phase relations.
Recordings were made from the directly visualized dorsal hippocampus of urethane-anesthetized rats with silver ball and tungsten microelectrodes. Theta of about 5 c/sec was elicited by reticular stimulation and was located in two broad strata in and subjacent to CA1. A superficial generator yielded...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1979
|
| _version_ | 1826288450575269888 |
|---|---|
| author | Green, K Rawlins, J |
| author_facet | Green, K Rawlins, J |
| author_sort | Green, K |
| collection | OXFORD |
| description | Recordings were made from the directly visualized dorsal hippocampus of urethane-anesthetized rats with silver ball and tungsten microelectrodes. Theta of about 5 c/sec was elicited by reticular stimulation and was located in two broad strata in and subjacent to CA1. A superficial generator yielded 200-250 microV theta from the alveus, stratum oriens and stratum pyramidale; a null-theta and phase-reversal point was located in stratum radiatum; a deep generator yielded 300-500 microV theta in stratum lacunosum-moleculare of the hippocampus and distal stratum moleculare of the dentate gyrus, with maximum amplitude near the fissure. No theta was found in CA3. Cross-correlation analyses between generators yielded coefficients on the order of -0.80 while within a generator--especially the deep one--coefficients could reach +0.95. Phase analyses showed the two generators were about 180 degrees out of phase, with the deep generator leading. Septotemporal movement along the upper generator yielded no phase shifts; similar movement along the deep generator showed slight lead ing in septal portions. Subiculofimbrial movement in both generators showed a complex pattern of phase shifts: generally, subicular sites led fimbrial sites, but an inversion of 10 degrees-20 degrees occurred in the millimeter anterior to the center of the hippocampus. Anatomical, phase and other datal led to consideration of a possible retrohippocampal role in supplementing the well-known pacemaker in the medial septum. |
| first_indexed | 2024-03-07T02:13:53Z |
| format | Journal article |
| id | oxford-uuid:a1909af2-4beb-49a3-b98c-775bd7bb2da4 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:13:53Z |
| publishDate | 1979 |
| record_format | dspace |
| spelling | oxford-uuid:a1909af2-4beb-49a3-b98c-775bd7bb2da42022-03-27T02:14:04ZHippocampal theta in rats under urethane: generators and phase relations.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a1909af2-4beb-49a3-b98c-775bd7bb2da4EnglishSymplectic Elements at Oxford1979Green, KRawlins, JRecordings were made from the directly visualized dorsal hippocampus of urethane-anesthetized rats with silver ball and tungsten microelectrodes. Theta of about 5 c/sec was elicited by reticular stimulation and was located in two broad strata in and subjacent to CA1. A superficial generator yielded 200-250 microV theta from the alveus, stratum oriens and stratum pyramidale; a null-theta and phase-reversal point was located in stratum radiatum; a deep generator yielded 300-500 microV theta in stratum lacunosum-moleculare of the hippocampus and distal stratum moleculare of the dentate gyrus, with maximum amplitude near the fissure. No theta was found in CA3. Cross-correlation analyses between generators yielded coefficients on the order of -0.80 while within a generator--especially the deep one--coefficients could reach +0.95. Phase analyses showed the two generators were about 180 degrees out of phase, with the deep generator leading. Septotemporal movement along the upper generator yielded no phase shifts; similar movement along the deep generator showed slight lead ing in septal portions. Subiculofimbrial movement in both generators showed a complex pattern of phase shifts: generally, subicular sites led fimbrial sites, but an inversion of 10 degrees-20 degrees occurred in the millimeter anterior to the center of the hippocampus. Anatomical, phase and other datal led to consideration of a possible retrohippocampal role in supplementing the well-known pacemaker in the medial septum. |
| spellingShingle | Green, K Rawlins, J Hippocampal theta in rats under urethane: generators and phase relations. |
| title | Hippocampal theta in rats under urethane: generators and phase relations. |
| title_full | Hippocampal theta in rats under urethane: generators and phase relations. |
| title_fullStr | Hippocampal theta in rats under urethane: generators and phase relations. |
| title_full_unstemmed | Hippocampal theta in rats under urethane: generators and phase relations. |
| title_short | Hippocampal theta in rats under urethane: generators and phase relations. |
| title_sort | hippocampal theta in rats under urethane generators and phase relations |
| work_keys_str_mv | AT greenk hippocampalthetainratsunderurethanegeneratorsandphaserelations AT rawlinsj hippocampalthetainratsunderurethanegeneratorsandphaserelations |