Enantioconvergent nucleophilic substitution via synergistic phase-transfer catalysis

Enantioconvergent nucleophilic substitution via synergistic phase-transfer catalysis

Catalytic enantioconvergent nucleophilic substitution reactions of alkyl halides are highly valuable transformations, but they are notoriously difficult to implement. Specifically, nucleophilic fluorination is a renowned challenge, especially when inexpensive alkali metal fluorides are used as fluor...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Dooley, C, Ibba, F, Botlik, BB, Palladino, C, Goult, CA, Gao, Y, Lister, A, Paton, RS, Lloyd-Jones, GC, Gouverneur, V
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Nature Research 2025

Eitemau Tebyg

Enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction by chiral phase-transfer catalysis
gan: Zhang, Xin
Cyhoeddwyd: (2019)

Enantioconvergent catalysis
gan: Justin T. Mohr, et al.
Cyhoeddwyd: (2016-09-01)

An enantioconvergent halogenophilic nucleophilic substitution (SN2X) reaction
gan: Zhang, Xin, et al.
Cyhoeddwyd: (2021)

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis
gan: Pupo, G, et al.
Cyhoeddwyd: (2018)

Transition metal catalysis and nucleophilic fluorination.
gan: Hollingworth, C, et al.
Cyhoeddwyd: (2012)

Regiodivergent nucleophilic fluorination under hydrogen bonding catalysis: a computational and experimental study
gan: Horwitz, MA, et al.
Cyhoeddwyd: (2023)

Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis
gan: Cheang, DMJ, et al.
Cyhoeddwyd: (2020)

Formal enantioconvergent substitution of alkyl halides via catalytic asymmetric photoredox radical coupling
gan: Jiangtao Li, et al.
Cyhoeddwyd: (2018-06-01)

Nucleophilic substitution/
gan: 235144 Barlin, G. B.
Cyhoeddwyd: (1975)

Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes
gan: Gregory C. Fu
Cyhoeddwyd: (2017-06-01)

Nucleophilic aliphatic substitution/
gan: 224038 Stevens, I. D. R.
Cyhoeddwyd: (1972)

Nucleophilic aliphatic substitution/
gan: 224038 Stevens, I. D. R.
Cyhoeddwyd: (1973)

Asymmetric azidation under hydrogen bonding phase-transfer catalysis: a combined experimental and computational study
gan: Wang, J, et al.
Cyhoeddwyd: (2022)

Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles
gan: Reece Jacques, et al.
Cyhoeddwyd: (2019-01-01)

Mechanisms of nucleophilic substitutions of acetals
gan: Bull, S, et al.
Cyhoeddwyd: (1998)

Vicarious Nucleophilic Substitution of Hydrogen
gan: Mieczysław Mąkosza
Cyhoeddwyd: (1994-11-01)

Ionic Liquids Catalysis for Carbon Dioxide Conversion With Nucleophiles
gan: Shu-Mei Xia, et al.
Cyhoeddwyd: (2018-10-01)

Counterion-mediated enantioconvergent synthesis of axially chiral medium rings
gan: Du, J-Y, et al.
Cyhoeddwyd: (2022)

Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles
gan: Jacques, R, et al.
Cyhoeddwyd: (2019)

Clarification of the stereochemical course of nucleophilic substitution of arylsulfonate-based nucleophile assisting leaving groups.
gan: Braddock, D, et al.
Cyhoeddwyd: (2009)

Regiodivergent nucleophilic fluorination under hydrogen bonding phase transfer catalysis
gan: Afratis, K
Cyhoeddwyd: (2021)

Micellar Effects on Nucleophilic Addition Reaction and Applicability of Enzyme Catalysis Model
gan: R. K. London Singh
Cyhoeddwyd: (2012-01-01)

Characterization of (chloronitrobenzil) sulfones in the vicarious nucleophilic substitution
gan: Alejandra Castellanos L., et al.
Cyhoeddwyd: (2016-12-01)

Transetherification on polyols by intra- and intermolecular nucleophilic substitutions.
gan: Takahiro Muraoka, et al.
Cyhoeddwyd: (2014-01-01)

Mesoporous Silica for Triphase Nucleophilic Substitution Reactions
gan: Shouai Feng, et al.
Cyhoeddwyd: (2018-08-01)

Site-selective modification of peptides using rhodium and palladium catalysis: complementary electrophilic and nucleophilic arylation.
gan: Chapman, C, et al.
Cyhoeddwyd: (2007)

Hydrogen bonding phase-transfer catalysis with Potassium Fluoride: enantioselective synthesis of β-fluoroamines
gan: Pupo, G, et al.
Cyhoeddwyd: (2019)

Multigram synthesis of N-alkyl bis-ureas for asymmetric hydrogen bonding phase-transfer catalysis
gan: Vicini, AC, et al.
Cyhoeddwyd: (2021)

A quantitative study of the halogenophilic nucleophilic substitution (SN2X) reaction and chalcogenophilic nucleophilic substitution (SN2Ch) reaction
gan: Kuo, Lun-Hsin, et al.
Cyhoeddwyd: (2025)

Photoredox Nucleophilic (Radio)fluorination of Alkoxyamines
gan: Ortalli, S, et al.
Cyhoeddwyd: (2024)

Progress in nucleophilic catalysis and development of nickel-catalyzed cross-couplings of propargylic halides
gan: Smith, Sean W. (Sean Wesley)
Cyhoeddwyd: (2009)

Nucleophilic aromatization of monoterpenes from isoprene under nickel/iodine cascade catalysis
gan: Wei-Song Zhang, et al.
Cyhoeddwyd: (2023-11-01)

Guanidine-copper complex catalyzed allylic borylation for the enantioconvergent synthesis of tertiary cyclic allylboronates
gan: Ge, Yicen, et al.
Cyhoeddwyd: (2021)

Hydrogen bonding phase-transfer catalysis with ionic reactants: enantioselective synthesis of γ-fluoroamines
gan: Roagna, G, et al.
Cyhoeddwyd: (2020)

An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents
gan: Ibis Cemil, et al.
Cyhoeddwyd: (2015-01-01)

Roundabout Mechanism of Ion–Molecule Nucleophilic Substitution Reactions
gan: Xiangyu Wu, et al.
Cyhoeddwyd: (2024-09-01)

Transetherification of 2,4-dimethoxynitrobenzene by aromatic nucleophilic substitution.
gan: Jiho Song, et al.
Cyhoeddwyd: (2017-01-01)

Asymmetric Synthesis of Stereogenic Phosphorus P(V) Centers Using Chiral Nucleophilic Catalysis
gan: Ahmed Numan, et al.
Cyhoeddwyd: (2021-06-01)

Chelation enables selectivity control in enantioconvergent Suzuki–Miyaura cross-couplings on acyclic allylic systems
gan: Stojalnikova, V, et al.
Cyhoeddwyd: (2024)

Enantioconvergent synthesis of axially chiral amides enabled by Pd-catalyzed dynamic kinetic asymmetric aminocarbonylation
gan: Lei Su, et al.
Cyhoeddwyd: (2024-08-01)