Enantioconvergent nucleophilic substitution via synergistic phase-transfer catalysis
Catalytic enantioconvergent nucleophilic substitution reactions of alkyl halides are highly valuable transformations, but they are notoriously difficult to implement. Specifically, nucleophilic fluorination is a renowned challenge, especially when inexpensive alkali metal fluorides are used as fluor...
Hauptverfasser: | Dooley, C, Ibba, F, Botlik, BB, Palladino, C, Goult, CA, Gao, Y, Lister, A, Paton, RS, Lloyd-Jones, GC, Gouverneur, V |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Nature Research
2025
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