The voltammetric determination of peroxynitrite at a mercury film electrode
This report describes the direct voltammetric detection of peroxynitrite (PN, ONOO-), an important analyte in many physiological biochemical pathways, at a mercury film electrode (MFE) at alkaline pH. The voltammetric response of PN is observed as a cathodic inverted peak when the potential is swept...
| প্রধান লেখক: | , , , , |
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| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
2007
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| _version_ | 1826288475781988352 |
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| author | Zakharova, E Yurmazova, T Nazarov, B Wildgoose, G Compton, R |
| author_facet | Zakharova, E Yurmazova, T Nazarov, B Wildgoose, G Compton, R |
| author_sort | Zakharova, E |
| collection | OXFORD |
| description | This report describes the direct voltammetric detection of peroxynitrite (PN, ONOO-), an important analyte in many physiological biochemical pathways, at a mercury film electrode (MFE) at alkaline pH. The voltammetric response of PN is observed as a cathodic inverted peak when the potential is swept in the oxidative direction at ca. -0.1 V vs. a Ag/AgCl/1 M KCl reference electrode. An mechanism is proposed to explain this behaviour involving the initial formation of a thin film of Hg(i) oxide on the electrode which is then oxidised by PN to form HgO in a chemical step. The HgO is then reduced back to Hg(0) at the electrode potential of interest resulting in a net cathodic current. The parameters affecting the voltammetry of PN at a MFE, including the concentration of PN (10-5-10-4 M), the effect of varying scan rate (5-100 mV s-1) and pH are investigated and the kinetics of PN decay in alkaline solutions ranging from pH 9-13 are explored electrochemically. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. |
| first_indexed | 2024-03-07T02:14:16Z |
| format | Journal article |
| id | oxford-uuid:a1aecf26-3b9b-437e-9ffa-a6f9f2a334b8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:14:16Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:a1aecf26-3b9b-437e-9ffa-a6f9f2a334b82022-03-27T02:14:56ZThe voltammetric determination of peroxynitrite at a mercury film electrodeJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a1aecf26-3b9b-437e-9ffa-a6f9f2a334b8EnglishSymplectic Elements at Oxford2007Zakharova, EYurmazova, TNazarov, BWildgoose, GCompton, RThis report describes the direct voltammetric detection of peroxynitrite (PN, ONOO-), an important analyte in many physiological biochemical pathways, at a mercury film electrode (MFE) at alkaline pH. The voltammetric response of PN is observed as a cathodic inverted peak when the potential is swept in the oxidative direction at ca. -0.1 V vs. a Ag/AgCl/1 M KCl reference electrode. An mechanism is proposed to explain this behaviour involving the initial formation of a thin film of Hg(i) oxide on the electrode which is then oxidised by PN to form HgO in a chemical step. The HgO is then reduced back to Hg(0) at the electrode potential of interest resulting in a net cathodic current. The parameters affecting the voltammetry of PN at a MFE, including the concentration of PN (10-5-10-4 M), the effect of varying scan rate (5-100 mV s-1) and pH are investigated and the kinetics of PN decay in alkaline solutions ranging from pH 9-13 are explored electrochemically. © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. |
| spellingShingle | Zakharova, E Yurmazova, T Nazarov, B Wildgoose, G Compton, R The voltammetric determination of peroxynitrite at a mercury film electrode |
| title | The voltammetric determination of peroxynitrite at a mercury film electrode |
| title_full | The voltammetric determination of peroxynitrite at a mercury film electrode |
| title_fullStr | The voltammetric determination of peroxynitrite at a mercury film electrode |
| title_full_unstemmed | The voltammetric determination of peroxynitrite at a mercury film electrode |
| title_short | The voltammetric determination of peroxynitrite at a mercury film electrode |
| title_sort | voltammetric determination of peroxynitrite at a mercury film electrode |
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