Recombination hotspots and population structure in Plasmodium falciparum.

Understanding the influences of population structure, selection, and recombination on polymorphism and linkage disequilibrium (LD) is integral to mapping genes contributing to drug resistance or virulence in Plasmodium falciparum. The parasite's short generation time, coupled with a high cross-...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mu, J, Awadalla, P, Duan, J, McGee, K, Joy, D, McVean, G, Su, X
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2005