Effects of simvastatin on plasma lipoproteins and response to arterial injury in wild-type and apolipoprotein-E-deficient mice.
OBJECTIVE: To test the non-lipid-lowering effects of simvastatin on the response to injury in normolipidemic and hyperlipidemic mice. METHODS AND RESULTS: Wild-type (WT) mice (n = 40) and hyperlipidemic apolipoprotein-E-deficient (apoE(-/-)) mice (n = 40) received normal chow or chow containing sim...
Main Authors: | Choudhury, R, Carrelli, A, Stern, J, Chereshnev, I, Soccio, R, Elmalem, V, Fallon, J, Fisher, E, Reis, E |
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Format: | Journal article |
Language: | English |
Published: |
2004
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