Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.
Pretreatment of pancreatic beta cells with pertussis toxin resulted in a 30% increase in peak whole-cell Ca2+ currents recorded in the absence of exogenous intracellular guanine nucleotides. Intracellular application of 90 microM GTP[gamma S], by liberation from a caged precursor, resulted in 40% re...
Những tác giả chính: | Ammälä, C, Berggren, P, Bokvist, K, Rorsman, P |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
1992
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