Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.
Pretreatment of pancreatic beta cells with pertussis toxin resulted in a 30% increase in peak whole-cell Ca2+ currents recorded in the absence of exogenous intracellular guanine nucleotides. Intracellular application of 90 microM GTP[gamma S], by liberation from a caged precursor, resulted in 40% re...
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
1992
|