An update on the genetics of colorectal cancer.
Colorectal carcinoma (CRC) remains a frequent cause of cancer-associated mortality in the UK and still has a relatively poor outcome. Single gene defects account for up to 2-6% of cases, but twin studies suggest a hereditary component in 35%. CRC represents a paradigm for cancer genetics. Almost all...
Main Authors: | Kemp, Z, Thirlwell, C, Sieber, O, Silver, A, Tomlinson, I |
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Format: | Journal article |
Language: | English |
Published: |
2004
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