Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.
The WTCCC study identified 49 SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-4) - 1 x 10(-5) (tier 3). Here we show that three of these SNPs, mapping to chromosome 10p15 (rs4750316), 12q13 (rs1678542) and 22q13 (rs3218253), are also associated (trend P = 4 x 10(-5), P = 4 x 10(-...
Auteurs principaux: | Barton, A, Thomson, W, Ke, X, Eyre, S, Hinks, A, Bowes, J, Plant, D, Gibbons, L, Wilson, A, Bax, D, Morgan, A, Emery, P, Steer, S, Hocking, L, Reid, D, Wordsworth, P, Harrison, P, Worthington, J |
---|---|
Format: | Journal article |
Langue: | English |
Publié: |
2008
|
Documents similaires
-
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
par: Orozco, G, et autres
Publié: (2009) -
Corrigendum: Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23
par: Orozco, G, et autres
Publié: (2010) -
Rheumatoid arthritis association at 6q23.
par: Thomson, W, et autres
Publié: (2007) -
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23 (vol 18, pg 2693, 2009)
par: Orozco, G, et autres
Publié: (2010) -
Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.
par: McClure, A, et autres
Publié: (2009)