Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

PURPOSE: Hypoxia-inducible factors HIF1alpha and HIF2alpha (HIFalphas) regulate the expression of a variety of genes encoding proteins related to angiogenesis and to anaerobic metabolism of cells exposed to hypoxic stress. Their putative role as markers of clinically relevant hypoxia and, therefore...

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Detalhes bibliográficos
Principais autores:	Koukourakis, M, Giatromanolaki, A, Sivridis, E, Simopoulos, C, Turley, H, Talks, K, Gatter, K, Harris, A
Formato:	Journal article
Idioma:	English
Publicado em:	2002

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