Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

PURPOSE: Hypoxia-inducible factors HIF1alpha and HIF2alpha (HIFalphas) regulate the expression of a variety of genes encoding proteins related to angiogenesis and to anaerobic metabolism of cells exposed to hypoxic stress. Their putative role as markers of clinically relevant hypoxia and, therefore...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Koukourakis, M, Giatromanolaki, A, Sivridis, E, Simopoulos, C, Turley, H, Talks, K, Gatter, K, Harris, A
Format:	Journal article
Sprache:	English
Veröffentlicht:	2002

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