Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.
PURPOSE: Hypoxia-inducible factors HIF1alpha and HIF2alpha (HIFalphas) regulate the expression of a variety of genes encoding proteins related to angiogenesis and to anaerobic metabolism of cells exposed to hypoxic stress. Their putative role as markers of clinically relevant hypoxia and, therefore...
Váldodahkkit: | Koukourakis, M, Giatromanolaki, A, Sivridis, E, Simopoulos, C, Turley, H, Talks, K, Gatter, K, Harris, A |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2002
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Geahča maid
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High DLL4 expression in tumour-associated vessels predicts for favorable radiotherapy outcome in locally advanced squamous cell head-neck cancer (HNSCC).
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