Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

PURPOSE: Hypoxia-inducible factors HIF1alpha and HIF2alpha (HIFalphas) regulate the expression of a variety of genes encoding proteins related to angiogenesis and to anaerobic metabolism of cells exposed to hypoxic stress. Their putative role as markers of clinically relevant hypoxia and, therefore...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Koukourakis, M, Giatromanolaki, A, Sivridis, E, Simopoulos, C, Turley, H, Talks, K, Gatter, K, Harris, A
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2002