Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer.

PURPOSE: Hypoxia-inducible factors HIF1alpha and HIF2alpha (HIFalphas) regulate the expression of a variety of genes encoding proteins related to angiogenesis and to anaerobic metabolism of cells exposed to hypoxic stress. Their putative role as markers of clinically relevant hypoxia and, therefore...

Полное описание

Библиографические подробности
Главные авторы: Koukourakis, M, Giatromanolaki, A, Sivridis, E, Simopoulos, C, Turley, H, Talks, K, Gatter, K, Harris, A
Формат: Journal article
Язык:English
Опубликовано: 2002