YAP dysregulation by phosphorylation or Δnp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets
Overexpression of the Yes-associated protein (YAP), and TP53 family members ΔNp63 and p73, have been independently detected in subsets of head and neck squamous cell carcinomas (HNSCCs). YAP may serve as a nuclear cofactor with ΔNp63 and p73, but the functional role of YAP and their potential relati...
Hauptverfasser: | , , , , , , , , , , , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2010
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