YAP dysregulation by phosphorylation or Δnp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets

Overexpression of the Yes-associated protein (YAP), and TP53 family members ΔNp63 and p73, have been independently detected in subsets of head and neck squamous cell carcinomas (HNSCCs). YAP may serve as a nuclear cofactor with ΔNp63 and p73, but the functional role of YAP and their potential relati...

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Bibliographische Detailangaben
Hauptverfasser: Ehsanian, R, Brown, M, Lu, H, Yang, X, Pattatheyil, A, Yan, B, Duggal, P, Chuang, R, Doondeea, J, Feller, S, Sudol, M, Chen, Z, Van Waes, C
Format: Journal article
Sprache:English
Veröffentlicht: 2010