Human herpesvirus 8 K14 protein mimics CD200 in down-regulating macrophage activation through CD200 receptor.
Many viral proteins limit host immune defenses, and their genes often originate from their hosts. CD200 (OX2) is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) that is implicated in locally preventing macrophage activation. Distant, but recog...
Main Authors: | Foster-Cuevas, M, Wright, G, Puklavec, M, Brown, M, Barclay, N |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2004
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