Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.

Urinary glycoproteins are important inhibitors of calcium oxalate crystallization and adhesion of crystals to renal cells, both of which are key mechanisms in kidney stone formation. This has been attributed to glycosylation of the proteins. In South Africa, the black population rarely form stones (...

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Bibliographic Details
Main Authors: Webber, D, Radcliffe, C, Royle, L, Tobiasen, G, Merry, A, Rodgers, A, Sturrock, E, Wormald, M, Harvey, D, Dwek, R, Rudd, P
Format: Journal article
Language:English
Published: 2006