Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

<p><strong>Background:</strong> The characterisation of the peripheral immune system in the autoimmune disease systemic lupus erythematosus (SLE) at the single-cell level has been limited by the reduced sensitivity of current whole-transcriptomic technologies. Here we employ a targ...

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Bibliographic Details
Main Authors: Trzupek, D, Lee, M, Hamey, F, Wicker, LS, Todd, JA, Ferreira, RC
Format: Journal article
Language:English
Published: F1000Research 2021