Lipid interactions of a ciliary membrane TRP channel: simulation and structural studies of Polycystin-2 (PC2)

Lipid interactions of a ciliary membrane TRP channel: simulation and structural studies of Polycystin-2 (PC2)

Polycystin-2 (PC2) is a transient receptor potential (TRP) channel present in ciliary membranes of the kidney. PC2 shares a transmembrane fold with other TRP channels, in addition to an extracellular domain found in TRPP and TRPML channels. Using molecular dynamics (MD) simulations and cryoelectron...

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Bibliographic Details
Main Authors:	Wang, Q, Corey, R, Hedger, G, Aryal, P, Grieben, M, Nasrallah, C, Baronina, A, Pike, A, Shi, J, Carpenter, E, Sansom, M
Format:	Journal article
Language:	English
Published:	Cell Press 2019

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