Lipid interactions of a ciliary membrane TRP channel: simulation and structural studies of Polycystin-2 (PC2)

Polycystin-2 (PC2) is a transient receptor potential (TRP) channel present in ciliary membranes of the kidney. PC2 shares a transmembrane fold with other TRP channels, in addition to an extracellular domain found in TRPP and TRPML channels. Using molecular dynamics (MD) simulations and cryoelectron...

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Những tác giả chính: Wang, Q, Corey, R, Hedger, G, Aryal, P, Grieben, M, Nasrallah, C, Baronina, A, Pike, A, Shi, J, Carpenter, E, Sansom, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Cell Press 2019