Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta.

Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta.

Hematopoietic stem cells (HSCs) are first detected in the floor of the embryonic dorsal aorta (DA), and we investigate the signals that induce the HSC program there. We show that while continued Hedgehog (Hh) signaling from the overlying midline structures maintains the arterial program characterist...

Full description

Bibliographic Details
Main Authors: Wilkinson, R, Pouget, C, Gering, M, Russell, A, Davies, S, Kimelman, D, Patient, R
Format: Journal article
Language:English
Published: 2009

Similar Items

Similar Items