T cell activation is determined by the number of presented antigens.
Antigen recognition is a key event during T cell activation. Here, we introduce nanopatterned antigen arrays that mimic the antigen presenting cell surface during T cell activation. The assessment of activation related events revealed the requirement of a minimal density of 90-140 stimulating major...
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Bibliographic Details
| Main Authors: |
Deeg, J,
Axmann, M,
Matic, J,
Liapis, A,
Depoil, D,
Afrose, J,
Curado, S,
Dustin, M,
Spatz, J |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2013
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