T cell activation is determined by the number of presented antigens.
Antigen recognition is a key event during T cell activation. Here, we introduce nanopatterned antigen arrays that mimic the antigen presenting cell surface during T cell activation. The assessment of activation related events revealed the requirement of a minimal density of 90-140 stimulating major...
Autori principali: | Deeg, J, Axmann, M, Matic, J, Liapis, A, Depoil, D, Afrose, J, Curado, S, Dustin, M, Spatz, J |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2013
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