T cell activation is determined by the number of presented antigens.

Antigen recognition is a key event during T cell activation. Here, we introduce nanopatterned antigen arrays that mimic the antigen presenting cell surface during T cell activation. The assessment of activation related events revealed the requirement of a minimal density of 90-140 stimulating major...

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Dettagli Bibliografici
Autori principali: Deeg, J, Axmann, M, Matic, J, Liapis, A, Depoil, D, Afrose, J, Curado, S, Dustin, M, Spatz, J
Natura: Journal article
Lingua:English
Pubblicazione: 2013

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