Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults

A few prospective studies have suggested that tea, alcohol, and fruit consumption may reduce the risk of kidney stones. However, little is known whether such associations and their combined effect persist in Chinese adults, for whom the popular tea and alcohol drinks are different from those investi...

Full description

Bibliographic Details
Main Authors: Wang, H, Fan, J, Yu, C, Guo, Y, Pei, P, Yang, L, Chen, Y, Du, H, Meng, F, Chen, J, Chen, Z, Lv, J, Li, L
Other Authors: On Behalf Of The China Kadoorie Biobank Collaborative Group
Format: Journal article
Language:English
Published: MDPI 2021
_version_ 1797086081975320576
author Wang, H
Fan, J
Yu, C
Guo, Y
Pei, P
Yang, L
Chen, Y
Du, H
Meng, F
Chen, J
Chen, Z
Lv, J
Li, L
author2 On Behalf Of The China Kadoorie Biobank Collaborative Group
author_facet On Behalf Of The China Kadoorie Biobank Collaborative Group
Wang, H
Fan, J
Yu, C
Guo, Y
Pei, P
Yang, L
Chen, Y
Du, H
Meng, F
Chen, J
Chen, Z
Lv, J
Li, L
author_sort Wang, H
collection OXFORD
description A few prospective studies have suggested that tea, alcohol, and fruit consumption may reduce the risk of kidney stones. However, little is known whether such associations and their combined effect persist in Chinese adults, for whom the popular tea and alcohol drinks are different from those investigated in the aforementioned studies. The present study included 502,621 participants from the China Kadoorie Biobank (CKB). Information about tea, alcohol, and fruit consumption was self-reported at baseline. The first documented cases of kidney stones during follow-up were collected through linkage with the national health insurance system. Cox regression was used to calculate the hazard ratio (HR) and 95% confidence interval (CI). During a median of 11.1 years of follow-up, we collected 12,407 cases of kidney stones. After multivariable adjustment, tea, alcohol, and fruit consumption were found to be negatively associated with kidney stone risk, but the linear trend was only found in tea and fruit consumption. Compared with non-tea consumers, the HR (95% CI) for participants who drank ≥7 cups of tea per day was 0.73 (0.65-0.83). Compared with non-alcohol consumers, the HR (95% CI) was 0.79 (0.72-0.87) for participants who drank pure alcohol of 30.0-59.9 g per day but had no further decrease with a higher intake of alcohol. Compared with less-than-weekly consumers, the HR (95% CI) for daily fruit consumers was 0.81 (0.75-0.87). Even for those who did not drink alcohol excessively, increasing tea and fruit consumption could also independently reduce the stone risk. Among Chinese adults, tea, alcohol, and fruit consumption was associated with a lower risk of kidney stones.
first_indexed 2024-03-07T02:16:57Z
format Journal article
id oxford-uuid:a295acf5-65f6-4a0e-8e6e-da51036afde1
institution University of Oxford
language English
last_indexed 2024-03-07T02:16:57Z
publishDate 2021
publisher MDPI
record_format dspace
spelling oxford-uuid:a295acf5-65f6-4a0e-8e6e-da51036afde12022-03-27T02:21:11ZConsumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adultsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a295acf5-65f6-4a0e-8e6e-da51036afde1EnglishSymplectic ElementsMDPI2021Wang, HFan, JYu, CGuo, YPei, PYang, LChen, YDu, HMeng, FChen, JChen, ZLv, JLi, LOn Behalf Of The China Kadoorie Biobank Collaborative GroupA few prospective studies have suggested that tea, alcohol, and fruit consumption may reduce the risk of kidney stones. However, little is known whether such associations and their combined effect persist in Chinese adults, for whom the popular tea and alcohol drinks are different from those investigated in the aforementioned studies. The present study included 502,621 participants from the China Kadoorie Biobank (CKB). Information about tea, alcohol, and fruit consumption was self-reported at baseline. The first documented cases of kidney stones during follow-up were collected through linkage with the national health insurance system. Cox regression was used to calculate the hazard ratio (HR) and 95% confidence interval (CI). During a median of 11.1 years of follow-up, we collected 12,407 cases of kidney stones. After multivariable adjustment, tea, alcohol, and fruit consumption were found to be negatively associated with kidney stone risk, but the linear trend was only found in tea and fruit consumption. Compared with non-tea consumers, the HR (95% CI) for participants who drank ≥7 cups of tea per day was 0.73 (0.65-0.83). Compared with non-alcohol consumers, the HR (95% CI) was 0.79 (0.72-0.87) for participants who drank pure alcohol of 30.0-59.9 g per day but had no further decrease with a higher intake of alcohol. Compared with less-than-weekly consumers, the HR (95% CI) for daily fruit consumers was 0.81 (0.75-0.87). Even for those who did not drink alcohol excessively, increasing tea and fruit consumption could also independently reduce the stone risk. Among Chinese adults, tea, alcohol, and fruit consumption was associated with a lower risk of kidney stones.
spellingShingle Wang, H
Fan, J
Yu, C
Guo, Y
Pei, P
Yang, L
Chen, Y
Du, H
Meng, F
Chen, J
Chen, Z
Lv, J
Li, L
Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title_full Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title_fullStr Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title_full_unstemmed Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title_short Consumption of tea, alcohol, and fruits and risk of kidney stones: a prospective cohort study in 0.5 million Chinese adults
title_sort consumption of tea alcohol and fruits and risk of kidney stones a prospective cohort study in 0 5 million chinese adults
work_keys_str_mv AT wangh consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT fanj consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT yuc consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT guoy consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT peip consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT yangl consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT cheny consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT duh consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT mengf consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT chenj consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT chenz consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT lvj consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults
AT lil consumptionofteaalcoholandfruitsandriskofkidneystonesaprospectivecohortstudyin05millionchineseadults