Delayed AMPA receptor blockade reduces cerebral infarction induced by focal ischemia.

Delayed AMPA receptor blockade reduces cerebral infarction induced by focal ischemia.

The potent and selective AMPA receptor antagonist NBQX was tested for cytoprotective properties in an adult rat model of transient focal neocortical ischemia. Nineteen spontaneously hypertensive rats sustained 2 h of middle cerebral artery occlusion, followed by 22 h of recirculation. Ninety minutes...

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Bibliographic Details
Main Authors:	Buchan, A, Xue, D, Huang, Z, Smith, K, Lesiuk, H
Format:	Journal article
Language:	English
Published:	1991

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