Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the preferential loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction is increasingly appreciated as a key determinant of dopaminergic neuronal susceptibility in PD and is a feature...
Główni autorzy: | , , , |
---|---|
Format: | Journal article |
Język: | English |
Wydane: |
Elsevier
2015
|