Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the preferential loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction is increasingly appreciated as a key determinant of dopaminergic neuronal susceptibility in PD and is a feature...
Huvudupphovsmän: | Ryan, B, Hoek, S, Fon, E, Wade-Martins, R |
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Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
Elsevier
2015
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