Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles.
OBJECTIVES: Major histocompatibility complex class I (MHC-I) proteins exist at the cell surface in antigen presenting forms and as beta2m-independent free heavy chains (FHCs). FHCs have been implicated in spondyloarthritis, but little is known about their expression in healthy individuals. We studie...
Hauptverfasser: | Raine, T, Brown, D, Bowness, P, Hill Gaston, J, Moffett, A, Trowsdale, J, Allen, R |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2006
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