Amplified delivery of indium-111 to EGFR-positive human breast cancer cells.

A method is described to amplify the delivery of 111In to human breast cancer cells utilizing a novel human serum albumin-human EGF (HSA-hEGF) bioconjugate substituted preferentially in the HSA domain with multiple DTPA metal chelators for 111In. 111In-DTPA-HSA-hEGF exhibited a lower receptor-bindin...

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Detalles Bibliográficos
Autores principales: Wang, J, Chen, P, Su, Z, Vallis, K, Sandhu, J, Cameron, R, Hendler, A, Reilly, R
Formato: Journal article
Lenguaje:English
Publicado: 2001