A CONCISE APPROACH TO FUNCTIONALIZED, HOMOCHIRAL PYRROLIDINONES

Acylation of O,N-acetal 1 gives excellent yields of the C-7 substituted products 2a,b. Alkylation of 2a under mild conditions gives high yields of the exo- 3 and endo- 4 substituted products in varying ratios, depending on the alkylating agent. The unsaturated derivative 8 reacts in high yields unde...

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Main Authors: Bamford, M, Beard, M, Cherry, D, Moloney, M
格式: Journal article
语言:English
出版: 1995